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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. MDH1, malate dehydrogenase 1, NAD (soluble)
Sequence ID:NM_001199111
NM_001199112
NM_005917
Entrez Gene ID:4190
Ensembl ID:ENSG00000014641

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pineal gland, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, stem cell, stomach, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:2p13.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:2: 63816366 - 63834307

Transcript StartTranscript EndChromosomal Start Chromosomal End
1596381612163816179
601586382162163821719
1592556382255663822652
2564316382453263824707
4325546382630363826425
5557316383182963832005
7328456383241363832526
8469356383307263833161
93612686383399563834327

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3505345Full LengthBC001484malate dehydrogenase 1, NAD (soluble)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_005908  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001199111 NP_001186040      
NM_001199112 NP_001186041      
NM_005917 NP_005908 P40925 EC 1.1.1.96
EC 1.1.1.37
Ldh_1_N
Ldh_1_C

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
U20352 AAC16436 P40925 EC 1.1.1.96
EC 1.1.1.37
BC001484 AAH01484 P40925 EC 1.1.1.96
EC 1.1.1.37
D55654 BAA09513 P40925 EC 1.1.1.96
EC 1.1.1.37
AK312331 BAG35252 P40925 EC 1.1.1.96
EC 1.1.1.37
AK300719 BAG62394 P40925 EC 1.1.1.96
EC 1.1.1.37
AK295931 BAH12223 B7Z3I7  
CR457405 CAG33686 P40925 EC 1.1.1.96
EC 1.1.1.37

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens MDH1 NP_001186040 R.norvegicus Mdh1 24551   NP_150238 97
M.musculus Mdh1 17449 Gene Info NP_032644 96
A.gambiae AgaP_AGAP009510 1271401   XP_310186 67
D.melanogaster CG5362 34414   NP_609394 66
A.thaliana AT1G04410 839527   NP_171936 62
A.thaliana AT5G43330 834351   NP_199147 61
C.elegans F46E10.10 179041   NP_504656 60

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta