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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. DLST, dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)
Sequence ID:NM_001244883
RefSeqGene ID:NG_030313
Entrez Gene ID:1743
Ensembl ID:ENSG00000119689

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

Cytogenetic Location (from UniGene)

Cytogenetic Location:14q24.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:14: 75348595 - 75369314

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2820348Full LengthBC000302dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)
2820348Full LengthBC001922dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_001924  

Protein Infomation

NM_001244883 NP_001231812      
NM_001933 NP_001924 P36957 EC 2-oxoacid_dh

Related Sequences

L37418 AAB59629 P36957 EC
BC000302 AAH00302 P36957 EC
BC001922 AAH01922 P36957 EC
HQ448281 ADQ32761    
D16373 BAA03871 P36957 EC
D17297 BAA04130 Q6LEQ7  
AK289414 BAF82103 P36957 EC
AK299505 BAH13054 B7Z5W8  
AK300396 BAH13277 B7Z6J1  
AK316463 BAH14834 B7ZAZ8  
BX248276 CAD62604 Q86TW7  
BX248764 CAD66571 Q86TQ8  
BX248774 CAD66581 Q86SW4  
CR456727 CAG33008 Q6IBS5  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens DLST NP_001924 M.musculus Dlst 78920 Gene Info NP_084501 93
R.norvegicus Dlst 299201   NP_001006982 93
D.melanogaster CG5214 41360   NP_650064 65
A.gambiae AgaP_AGAP004055 1270895   XP_309608 63
C.elegans W02F12.5 179063   NP_504700 62
N.crassa NCU02438 3875590   XP_959443 55
A.thaliana AT5G55070 835598   NP_200318 52
A.thaliana AT4G26910 828798   NP_567761 52
S.pombe SPBC776.15c 2541170   NP_596331 51
S.cerevisiae KGD2 851726   NP_010432 49
P.falciparum PF13_0121 814092   XP_001349947 47

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)