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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. LTA4H, leukotriene A4 hydrolase
Sequence ID:NM_000895
NM_001256643
NM_001256644
Entrez Gene ID:4048
Ensembl ID:ENSG00000111144

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, retina, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:12q22Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:12: 96396767 - 96429419


Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
5502553Full LengthBC032528leukotriene A4 hydrolase

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000886  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_000895 NP_000886 P09960 EC 3.3.2.6 Peptidase_M1
NM_001256643 NP_001243572      
NM_001256644 NP_001243573      

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
J03459 AAA36176 P09960 EC 3.3.2.6
J02959 AAA36177 P09960 EC 3.3.2.6
BC032528 AAH32528 P09960 EC 3.3.2.6
BC036555 AAH36555 Q49AK0  
JF432734 ADZ15951    
AB209740 BAD92977 Q59ES1  
AK293630 BAG57086 B4DEH5  
AK298017 BAG60321 P09960 EC 3.3.2.6
AK301308 BAG62860 B4DVZ8  
CR457068 CAG33349 P09960 EC 3.3.2.6

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens LTA4H NP_000886 M.musculus Lta4h 16993 Gene Info NP_032543 93
R.norvegicus Lta4h 299732   NP_001025202 93
A.gambiae AgaP_AGAP009907 1279320   XP_319027 50
C.elegans protease 177123   NP_500385 48
C.elegans peptidase 178176   NP_001023056 47
D.melanogaster CG10602 35146   NP_609916 46
S.cerevisiae LAP2 855682   NP_014353 43
S.pombe SPCC1322.05c 2538917   NP_588133 42
N.crassa NCU06732 3876807   XP_960660 41

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)