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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. CCND1, cyclin D1
Sequence ID:NM_053056
RefSeqGene ID:NG_007375
Entrez Gene ID:595
Ensembl ID:ENSG00000110092

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, retina, skin, soft tissue, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
COLON CANCERAKT1
APC
APC
AURKA
AXIN2
BCL10
BUB1B
EP300
FGFR3
FLCN
MLH3
NRAS
ODC1
PDGFRL
PIK3CA
PIK3CA
PLA2G2A
PTPRJ
SMAD7
TLR2
TLR4
TP53
TP53
MULTIPLE MYELOMAIRF4
LIG4
VON HIPPEL-LINDAU DISEASE, MODIFICATION OFVHL

Cytogenetic Location (from UniGene)

Cytogenetic Location:11q13Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:11: 69467364 - 69469242

NM_053056 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
14076945587269456278
4086236945779869458013
6247836945859969458758
7849326946276169462909
93342886946588569469240

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3507598Full LengthBC001501cyclin D1
3508088Full LengthBC000076cyclin D1
4124540Full LengthBC014078cyclin D1
4650919Full LengthBC023620cyclin D1
5457963Full LengthBC025302cyclin D1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_444284  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_053056 NP_444284 P24385
Q6FI00
Cyclin_N
Cyclin_C

Related Sequences

 
mRNAGenPeptSwissProt
M64349 AAA52136 P24385
M73554 AAA58392 P24385
Q6FI00
BC000076 AAH00076 P24385
Q6FI00
BC001501 AAH01501 P24385
Q6FI00
BC014078 AAH14078 P24385
Q6FI00
BC023620 AAH23620 P24385
Q6FI00
BC025302 AAH25302 P24385
Q6FI00
BT019844 AAV38647 P24385
Q6FI00
BT019845 AAV38648 P24385
Q6FI00
AY830112 AAV91344 Q5MGB2
DQ891848 ABM82774  
DQ895038 ABM85964  
AK313136 BAG35955 Q6FI00
AK299044 BAG61118 B4DR06
X59798 CAA42470 P24385
Q6FI00
CR536538 CAG38775 P24385
Q6FI00
CR542099 CAG46896 P24385
Q6FI00
AM393193 CAL38071  
AM393430 CAL38308  
AM393593 CAL38470  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens CCND1 NP_444284 M.musculus Ccnd1 12443 Gene Info NP_031657 94
R.norvegicus Ccnd1 58919   NP_741989 94

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta