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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. RFWD2, Ring finger and WD repeat domain 2, E3 ubiquitin protein ligase
Sequence ID:NM_022457
Entrez Gene ID:64326
Ensembl ID:ENSG00000143207

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

Cytogenetic Location (from UniGene)

Cytogenetic Location:1q25.1-q25.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:1: 175914289 - 176176114

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
5271629Full LengthBC094728ring finger and WD repeat domain 2
4718123IncompleteBC020845ring finger and WD repeat domain 2
5244448IncompleteBC039723ring finger and WD repeat domain 2

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_001001740  NP_071902  

Protein Infomation

NM_001001740 NP_001001740   zf-C3HC4
NM_022457 NP_071902 Q8NHY2 zf-C3HC4

Related Sequences

BC020845 AAH20845 Q05CT6
BC094728 AAH94728 Q8NHY2
AF508940 AAM34692 Q8NHY2
AF527539 AAQ08989 Q8NHY2
AY509921 AAS82851 Q8NHY2
AK314750 BAG37289 Q8NHY2
AK001278 BAG50884 B3KM72

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens RFWD2 NP_071902 M.musculus Rfwd2 26374 Gene Info NP_036061 98
R.norvegicus LOC100360800 100360800   XP_002728072 96
A.thaliana COP1 817857   NP_180854 43

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)