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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. OAT, ornithine aminotransferase
Sequence ID:NM_000274
NM_001171814
RefSeqGene ID:NG_008861
Entrez Gene ID:4942
Ensembl ID:ENSG00000065154

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
GYRATE ATROPHY OF CHOROID AND RETINA WITH OR WITHOUTORNITHINEMIA 

Cytogenetic Location (from UniGene)

Cytogenetic Location:10q26Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:10: 126085878 - 126107476

 Exon Info From UCSC:
NM_000274
NM_001171814

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3449883Full LengthBC000964ornithine aminotransferase (gyrate atrophy)
3913352Full LengthBC016928ornithine aminotransferase (gyrate atrophy)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000265  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_000274 NP_000265 P04181 EC 2.6.1.13 Aminotran_3
NM_001171814 NP_001165285      

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
M23204 AAA36386 P04181 EC 2.6.1.13
M12267 AAA59956 P04181 EC 2.6.1.13
M14963 AAA59959 P04181 EC 2.6.1.13
S66421 AAB20297 P04181 EC 2.6.1.13
S66418 AAB20298 P04181 EC 2.6.1.13
BC000964 AAH00964 P04181 EC 2.6.1.13
BC016928 AAH16928 P04181 EC 2.6.1.13
JF432151 ADZ15368    
AB208817 BAD92054 Q59HE2  
AK312561 BAG35458 P04181 EC 2.6.1.13
AK296032 BAH12241 P04181 EC 2.6.1.13
AK315947 BAH14318 P04181 EC 2.6.1.13
Y07511 CAA68809 P04181 EC 2.6.1.13
CR457045 CAG33326 P04181 EC 2.6.1.13
CR749808 CAH18668 P04181 EC 2.6.1.13

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens OAT NP_000265 M.musculus Oat 18242 Gene Info NP_058674 91
R.norvegicus Oat 64313   NP_071966 91
A.gambiae AgaP_AGAP004793 1278432   XP_318019 73
D.melanogaster Oat 40145   NP_649139 72
C.elegans C16A3.10 175908   NP_741194 67
N.crassa NCU00194 3872557   XP_956417 58
S.pombe SPBC21C3.08c 2540626   NP_596588 58
P.falciparum PFF0435w 3885911   XP_966078 56
S.cerevisiae CAR2 851158   NP_013542 55
A.thaliana DELTA-OAT 834660   NP_199430 53

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta