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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. PSAP, prosaposin
Sequence ID:NM_001042465
NM_001042466
NM_002778
RefSeqGene ID:NG_009301
Entrez Gene ID:5660
Ensembl ID:ENSG00000197746

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pineal gland, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
COMBINED SAP DEFICIENCY 
GAUCHER DISEASE, ATYPICAL 
KRABBE DISEASE, ATYPICAL 
METACHROMATIC LEUKODYSTROPHY DUE TO SAP-B DEFICIENCY 

Cytogenetic Location (from UniGene)

Cytogenetic Location:10q21-q22Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:10: 73576961 - 73610987

 Exon Info From UCSC:
NM_001042465
NM_001042466
NM_002778

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3351606Full LengthBC007612prosaposin
3508263Full LengthBC001503prosaposin
3615413Full LengthBC004275prosaposin

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002769  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_001042465 NP_001035930    
NM_001042466 NP_001035931    
NM_002778 NP_002769 P07602 SapA
SapB_2
SapB_1

Related Sequences

 
mRNAGenPeptSwissProt
M60255 AAA36594 P07602
M60257 AAA36595 P07602
M60258 AAA36596 P07602
J03077 AAA52560 P07602
M32221 AAA60303 P07602
J03015 AAB59494 P07602
BC001503 AAH01503 P07602
BC004275 AAH04275 P07602
BC007612 AAH07612 P07602
BC091483 AAH91483 Q5BJH1
BT006849 AAP35495 P07602
DQ893009 ABM83935  
DQ896255 ABM87254  
D00422 BAA00321 P07602
AB209776 BAD93013 Q59EN5
AK223290 BAD97010 Q53FJ5
AK293672 BAG57116 B4DEK5
AK299184 BAG61229 B4DRB7
CR456746 CAG33027 P07602

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens PSAP NP_001035930 R.norvegicus Psap 25524   NP_037145 70
M.musculus Psap 19156 Gene Info NP_001139593 68
D.melanogaster Sap-r 43662   NP_524597 32
A.gambiae AgaP_AGAP001082 1278393   XP_317975 31

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)