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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. IRAK1, interleukin-1 receptor-associated kinase 1
Sequence ID:NM_001025242
RefSeqGene ID:NG_008387
Entrez Gene ID:3654
Ensembl ID:ENSG00000184216

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebrum, cervix, colon, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, stem cell, stomach, t-cell, testis, thymus, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:Xq28Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:X: 153277309 - 153285263

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4906853Full LengthBC014963interleukin-1 receptor-associated kinase 1
6164719Full LengthBC054000interleukin-1 receptor-associated kinase 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_001560  NP_001020413  NP_001020414  

Protein Infomation

NM_001025242 NP_001020413     Pkinase
NM_001025243 NP_001020414     Pkinase
NM_001569 NP_001560 P51617 EC Pkinase

Related Sequences

L76191 AAC41949 P51617 EC
BC014963 AAH14963 P51617 EC
BC054000 AAH54000 P51617 EC
AF346607 AAK62888 P51617 EC
DQ054788 AAY88246 P51617 EC
EU831520 ACE86439    
EU831427 ACE87114    
AM392624 CAL37502    
AM393211 CAL38089    

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens IRAK1 NP_001560 M.musculus Irak1 16179 Gene Info NP_001171446 81
R.norvegicus Irak1 363520   NP_001121027 81

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta