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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. ARHGEF6, Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
Sequence ID:NM_004840
RefSeqGene ID:NG_008873
Entrez Gene ID:9459
Ensembl ID:ENSG00000129675

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
MENTAL RETARDATION, X-LINKED 46 

Cytogenetic Location (from UniGene)

Cytogenetic Location:Xq26.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:X: 135863034 - 135864247

 Exon Info From UCSC:
NM_004840

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4510206Full LengthBC039856Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
6015396Full LengthBC043505Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
4344575IncompleteBC033768Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_004831  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_004840 NP_004831 Q15052 SH3_1
PH
CH
RhoGEF

Related Sequences

 
mRNAGenPeptSwissProt
AF207831 AAG27169 Q15052
BC033768 AAH33768 Q8N4Q3
BC039856 AAH39856 Q15052
BC043505 AAH43505 Q15052
D13631 BAA02796 Q15052
D25304 BAA04985 Q15052
AK291742 BAF84431 Q15052
AK294929 BAH11929 Q15052
AK295709 BAH12163 B7Z3C7
AK299861 BAH13153 B7Z667
BX537390 CAD97632 Q15052

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens ARHGEF6 NP_004831 M.musculus Arhgef6 73341 Gene Info NP_690014 92
R.norvegicus Arhgef6 363509   NP_001005565 92

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta