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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. TIMP1, TIMP metallopeptidase inhibitor 1
Sequence ID:NM_003254
RefSeqGene ID:NG_012533
Entrez Gene ID:7076
Ensembl ID:ENSG00000102265

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pineal gland, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:Xp11.3-p11.23Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:X: 47441711 - 47446187

NM_003254 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
11844744168947441872
1853134744280647442934
3143934744433447444413
3945204744460347444729
5216454744494147445065
6469154744591947446188

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3460153Full LengthBC000866TIMP metallopeptidase inhibitor 1
4272513IncompleteBC007097TIMP metallopeptidase inhibitor 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_003245  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_003254 NP_003245 Q6FGX5
P01033
TIMP

Related Sequences

 
mRNAGenPeptSwissProt
M12670 AAA52436 Q6FGX5
P01033
M59906 AAA63234 Q6FGX5
P01033
S68252 AAD14009 Q6FGX5
P01033
BC000866 AAH00866 Q6FGX5
P01033
DQ891122 ABM82048  
DQ894301 ABM85227  
AK311937 BAG34878 Q6FGX5
AK074854 BAG52016 B3KQF4
AK296116 BAG58865 B4DJK3
A10416 CAA00898 Q6FGX5
P01033
X02598 CAA26443 P01033
X03124 CAA26902 Q6FGX5
P01033
CR407638 CAG28566 Q6FGX5
P01033
CR541982 CAG46779 Q6FGX5
P01033

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens TIMP1 NP_003245 M.musculus Timp1 21857 Gene Info NP_001037849 75
R.norvegicus Timp1 116510   NP_446271 72

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta