Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
Genes
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. MUSK, muscle, skeletal, receptor tyrosine kinase
Sequence ID:NM_001166280
NM_001166281
NM_005592
RefSeqGene ID:NG_016016
Entrez Gene ID:4593
Ensembl ID:ENSG00000030304

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
MYASTHENIC SYNDROME, CONGENITAL, ASSOCIATED WITH ACETYLCHOLINE RECEPTOR DEFICIENCYCHRNB1
CHRNE
RAPSN

Cytogenetic Location (from UniGene)

Cytogenetic Location:9q31.3-q32Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:9: 113431138 - 113563278

 Exon Info From UCSC:
NM_001166280
NM_001166281
NM_005592

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
40034772Full LengthBC109098muscle, skeletal, receptor tyrosine kinase
40034773Full LengthBC109099muscle, skeletal, receptor tyrosine kinase

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_005583  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001166280 NP_001159752      
NM_001166281 NP_001159753      
NM_005592 NP_005583 O15146 EC 2.7.10.1 Fz
I-set
Pkinase_Tyr

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
AF006464 AAB63044 O15146 EC 2.7.10.1
BC109098 AAI09099 O15146 EC 2.7.10.1
BC109099 AAI09100 O15146 EC 2.7.10.1
EU832778 ACE87789    
EU832779 ACE87790    
GQ129313 ACT64447    
Z25436 CAA80923 Q15457  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens MUSK NP_005583 R.norvegicus Musk 81725   NP_112323 94
M.musculus Musk 18198 Gene Info NP_035074 93
D.melanogaster Nrk 36445   NP_477255 53
A.gambiae AgaP_AGAP006988 1270111   XP_308783 49

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta