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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. NEFL, Neurofilament, light polypeptide
Sequence ID:NM_006158
RefSeqGene ID:NG_008492
Entrez Gene ID:4747

Database Links

UniGeneEntrez GeneOMIMHPRDDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
CHARCOT-MARIE-TOOTH DISEASE, TYPE 1F 
CHARCOT-MARIE-TOOTH DISEASE, TYPE 2E 

Cytogenetic Location (from UniGene)

Cytogenetic Location:8p21Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:8: 24809901 - 24814127

NM_006158 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
1720112480847024810464
201220872481098824811063
208823312481106524811308
233224562481169424811818
245736022481298524814130

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4280159Full LengthBC039237neurofilament, light polypeptide
5264373Full LengthBC066952neurofilament, light polypeptide

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_006149  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_006158 NP_006149 P07196 Filament
Filament_head

Related Sequences

 
mRNAGenPeptSwissProt
BC039237 AAH39237 P07196
BC066952 AAH66952 I6L9F6
AY156690 AAN74826 P07196
DQ892646 ABM83572  
DQ895884 ABM86810  
AK075003 BAG52047 B3KQI5
AK127430 BAG54502 B3KXJ0
AK299095 BAG61155 B4DR43
AK296186 BAH12278 B7Z3P2
AL713644 CAD28456 Q8TCR7

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens NEFL NP_006149 R.norvegicus Nefl 83613   NP_113971 96
M.musculus Nefl 18039 Gene Info NP_035040 96

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)