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Gene Info

Gene Information For:Hs. AKR1B1, aldo-keto reductase family 1, member B1 (aldose reductase)
Sequence ID:NM_001628
Entrez Gene ID:231
Ensembl ID:ENSG00000085662

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pineal gland, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:7q35Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:7: 134127108 - 134143807

NM_001628 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
19434134127106134127521
435517134129989134130071
518601134132049134132132
602683134132731134132812
684790134133138134133244
791913134133748134133870
914991134134471134134548
9921108134135537134135653
11091276134136337134136504
12771416134143748134143887

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3357652Full LengthBC000260aldo-keto reductase family 1, member B1 (aldose reductase)
3960811Full LengthBC005387aldo-keto reductase family 1, member B1 (aldose reductase)
4049736Full LengthBC010391aldo-keto reductase family 1, member B1 (aldose reductase)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_001619  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001628 NP_001619 P15121 EC 1.1.1.21 Aldo_ket_red

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
M34720 AAA35560 P15121 EC 1.1.1.21
J04795 AAA51713 P15121 EC 1.1.1.21
J05017 AAA51714 P15121 EC 1.1.1.21
J05474 AAA51715 P15121 EC 1.1.1.21
BC000260 AAH00260 P15121 EC 1.1.1.21
BC005387 AAH05387 P15121 EC 1.1.1.21
BC010391 AAH10391 P15121 EC 1.1.1.21
AF328729 AAN09721 P15121 EC 1.1.1.21
BT019859 AAV38662 P15121 EC 1.1.1.21
DQ890758 ABM81684    
DQ892546 ABM83472    
DQ893921 ABM84847    
DQ895757 ABM86683    
AB209796 BAD93033 Q59EL5  
AK313439 BAG36230 P15121 EC 1.1.1.21
X15414 CAA33460 P15121 EC 1.1.1.21
CR450351 CAG29347 P15121 EC 1.1.1.21
CR542203 CAG47000 P15121 EC 1.1.1.21

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens AKR1B1 NP_001619 M.musculus Akr1b3 11677 Gene Info NP_033788 86
M.musculus LOC100504386 100504386   XP_003084494 86
R.norvegicus Akr1b1 24192   NP_036630 86
A.gambiae AgaP_AGAP011050 1269450   XP_308086 60
D.melanogaster CG6084 39304   NP_648484 59
C.elegans Y39G8B.1 175047   NP_496925 48
S.cerevisiae GRE3 856504   NP_011972 45
N.crassa NCU08384 3880080   XP_963931 44

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)