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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. MDH2, malate dehydrogenase 2, NAD (mitochondrial)
Sequence ID:NM_005918
Entrez Gene ID:4191
Ensembl ID:ENSG00000146701

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, pineal gland, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:7cen-q22

Chromosomal Position (from UCSC)

Chromosomal Position:7: 75677392 - 75695930

NM_005918 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2823443Full LengthBC001917malate dehydrogenase 2, NAD (mitochondrial)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_005909  

Protein Infomation

NM_005918 NP_005909 P40926 EC Ldh_1_N

Related Sequences

AF047470 AAC03787 P40926 EC
BC001917 AAH01917 P40926 EC
DQ402957 ABD77290 Q0QF37  
DQ893080 ABM84006    
DQ896341 ABM87340    
AK290779 BAF83468 P40926 EC
AK316587 BAG38175 P40926 EC
AK095803 BAG53133 B3KTM1  
AK293460 BAG56955 B4DE44  
CR536548 CAG38785 Q6FHZ0  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens MDH2 NP_005909 M.musculus Mdh2 17448 Gene Info NP_032643 95
R.norvegicus Mdh2 81829   NP_112413 94
A.gambiae AgaP_AGAP001903 1281223   XP_321163 66
D.melanogaster CG7998 42185   NP_650696 60
C.elegans mdh-1 175936   NP_498457 58
N.crassa NCU04899 3874555   XP_958408 58
A.thaliana mMDH1 841757   NP_564625 57
A.thaliana mMDH2 820731   NP_188120 57
S.cerevisiae MDH1 853777   NP_012838 55
S.pombe SPCC306.08c 2538766   NP_587816 52

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)