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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. CTSB, cathepsin B
Sequence ID:NM_001908
NM_147780
NM_147781
NM_147782
NM_147783
RefSeqGene ID:NG_009217
Entrez Gene ID:1508
Ensembl ID:ENSG00000164733

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:8p22Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:8: 11701828 - 11725627

 Exon Info From UCSC:
NM_001908
NM_147780
NM_147781
NM_147782
NM_147783

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4154307Full LengthBC010240cathepsin B
30334082Full LengthBC095408cathepsin B

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_680093  NP_680091  NP_680092  NP_001899  NP_680090  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001908 NP_001899 P07858 EC 3.4.22.1 Peptidase_C1
Propeptide_C1
NM_147780 NP_680090 P07858 EC 3.4.22.1 Peptidase_C1
Propeptide_C1
NM_147781 NP_680091 P07858 EC 3.4.22.1 Peptidase_C1
Propeptide_C1
NM_147782 NP_680092 P07858 EC 3.4.22.1 Peptidase_C1
Propeptide_C1
NM_147783 NP_680093 P07858 EC 3.4.22.1 Peptidase_C1
Propeptide_C1

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
M13230 AAA52125 P07858 EC 3.4.22.1
M14221 AAA52129 P07858 EC 3.4.22.1
L16510 AAC37547 P07858 EC 3.4.22.1
BC010240 AAH10240 P07858 EC 3.4.22.1
BC095408 AAH95408 P07858 EC 3.4.22.1
AK290239 BAF82928 A8K2H4  
AK075393 BAG52127 P07858 EC 3.4.22.1
AK092070 BAG52477 P07858 EC 3.4.22.1
AK097384 BAG53460 B3KUJ8  
AK296845 BAG59411 B4DL49  
AK297687 BAG60046 B4DMY4  
Y18460 CAA77178 Q6LAF9  
BX647765 CAI46053 Q5HYG5  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens CTSB NP_001899 M.musculus Ctsb 13030 Gene Info NP_031824 79
R.norvegicus Ctsb 64529   NP_072119 79
A.gambiae AgaP_AGAP004533 1274679   XP_313835 60
D.melanogaster CG10992 32341   NP_572920 60
A.thaliana AT1G02305 839538   NP_563648 53
A.thaliana AT4G01610 826792   NP_567215 52
A.thaliana AT1G02300 839576   NP_563647 50

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)