Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. ACTB, actin, beta
Sequence ID:NM_001101
RefSeqGene ID:NG_007992
Entrez Gene ID:60
Ensembl ID:ENSG00000075624

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pineal gland, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes

Cytogenetic Location (from UniGene)

Cytogenetic Location:7p22Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:7: 5566782 - 5570232

NM_001101 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2961617Full LengthBC002409actin, beta
3451917Full LengthBC001301actin, beta
3623067Full LengthBC004251actin, beta
3870487Full LengthBC014861actin, beta
4025526Full LengthBC013380actin, beta
4564532Full LengthBC016045actin, beta
3863361IncompleteBC012854actin, beta
3892332IncompleteBC009636actin, beta
4179564IncompleteBC008633actin, beta
40021898IncompleteBC113036actin, beta

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_001092  

Protein Infomation

NM_001101 NP_001092 P60709 Actin

Related Sequences

K00790 AAA51578 Q9UMN3
M28424 AAB16906 Q9UE89
BC001301 AAH01301 P60709
BC002409 AAH02409 P60709
BC004251 AAH04251 P60709
BC008633 AAH08633 P60709
BC012854 AAH12854 P60709
BC013380 AAH13380 P60709
BC014861 AAH14861 P60709
BC016045 AAH16045 P60709
BC113036 AAI13037 A0AUL6
DQ407611 ABD66582 A5GZ75
DQ471327 ABF01018 Q1KLZ0
EF095209 ABL01513 A1E282
DQ890960 ABM81886  
DQ894128 ABM85054  
EF036500 ABO65086 A4UCT3
D28354 BAA05720  
AK222925 BAD96645 Q53GK6
AK223032 BAD96752 Q53G99
AK223055 BAD96775 Q53G76
AK301372 BAG62914 B4DW52
AK304552 BAG65347 B4E335
AK316361 BAH14732 B7ZAP6
V00478 CAA23745 P60709
X00351 CAA25099 P60709
X63432 CAA45026 P60709

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens ACTB NP_001092 M.musculus Actb 11461 Gene Info NP_031419 100
R.norvegicus Actb 81822   NP_112406 100
A.gambiae AgaP_AGAP005095 1274770   XP_313971 97
D.melanogaster Act87E 48632   NP_731812 96
D.melanogaster Act57B 37368   NP_523800 95
A.thaliana ACT1 818339   NP_850284 90
A.thaliana ACT3 824542   NP_566988 90

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta