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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. SIM1, single-minded homolog 1 (Drosophila)
Sequence ID:NM_005068
RefSeqGene ID:NG_008230
Entrez Gene ID:6492
Ensembl ID:ENSG00000112246

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
OBESITYADRB2
ADRB3
AGRP
CARTPT
ENPP1
FTO
GHRL
MC3R
MC4R
NR0B2
POMC
PPARG
PPARGC1B
PYY
SDC3
UCP1
UCP2
UCP3
UCP3

Cytogenetic Location (from UniGene)

Cytogenetic Location:6q16.3-q21Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:6: 100838473 - 100912805

 Exon Info From UCSC:
NM_005068

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
40080751BC111931single-minded homolog 1 (Drosophila)
40080760BC118500single-minded homolog 1 (Drosophila)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_005059  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_005068 NP_005059 P81133 PAS
SIM_C
PAS_3

Related Sequences

 
mRNAGenPeptSwissProt
U70212 AAB62395 P81133
BC111931 AAI11932 P81133
BC118500 AAI18501  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens SIM1 NP_005059 M.musculus Sim1 20464 Gene Info NP_035506 97
R.norvegicus Sim1 309888   NP_001101111 96
A.gambiae AgaP_AGAP010058 1279488   XP_319213 73

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)