Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
Genes
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. EIF2AK1, eukaryotic translation initiation factor 2-alpha kinase 1
Sequence ID:NM_001134335
NM_014413
Entrez Gene ID:27102
Ensembl ID:ENSG00000086232

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:7p22Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:7: 6061879 - 6098785

 Exon Info From UCSC:
NM_001134335
NM_014413

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2989989Full LengthBC006524eukaryotic translation initiation factor 2-alpha kinase 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_055228  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001134335 NP_001127807      
NM_014413 NP_055228 Q9BQI3 EC 2.7.11.1 Pkinase

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
AF147094 AAF66736 Q9BQI3 EC 2.7.11.1
AF255050 AAF70289 Q9BQI3 EC 2.7.11.1
AF116634 AAF71057 Q9BQI3 EC 2.7.11.1
AF183414 AAG09683 Q9BQI3 EC 2.7.11.1
BC006524 AAH06524 Q9BQI3 EC 2.7.11.1
AF100784 AAP97223 Q9BQI3 EC 2.7.11.1
AB037790 BAA92607 Q9BQI3 EC 2.7.11.1
AK075192 BAC11461 Q9BQI3 EC 2.7.11.1
AK290327 BAF83016 Q9BQI3 EC 2.7.11.1
AK295712 BAG58556 B4DIP4  
AL136563 CAB66498 Q9BQI3 EC 2.7.11.1
AL834494 CAD39152 Q9BQI3 EC 2.7.11.1
AM392648 CAL37526    
AM393276 CAL38154    

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens EIF2AK1 NP_001127807 M.musculus Eif2ak1 15467 Gene Info NP_038585 83
R.norvegicus Eif2ak1 27137   NP_037355 82
S.pombe hri1 2541728   NP_594738 37
S.pombe hri2 2541943   NP_593146 35
A.gambiae AgaP_AGAP010925 1271026   XP_309768 31

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta