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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. HLA-DRA, major histocompatibility complex, class II, DR alpha
Sequence ID:NM_019111
RefSeqGene ID:NG_002392
Entrez Gene ID:3122
Ensembl ID:ENSG00000204287

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, colon, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pineal gland, placenta, pooled tissue, prostate, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:6p21.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:6: 32407656 - 32412813

NM_019111 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
5162925Full LengthBC071659major histocompatibility complex, class II, DR alpha
5214156Full LengthBC032350major histocompatibility complex, class II, DR alpha

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_061984  

Protein Infomation

NM_019111 NP_061984   MHC_II_alpha

Related Sequences

J00193 AAA36272 O19716
J00194 AAA36275 P01903
M35979 AAA36283 O19720
M60334 AAA59783 P01903
K01171 AAA59785 P01903
M60333 AAA59787 Q30118
BC032350 AAH32350 P01903
BC071659 AAH71659 P01903
DQ891595 ABM82521  
DQ894789 ABM85715  
AK313123 BAG35943 B0UXD8
AK297032 BAG59560 B4DLJ8
AK301134 BAG62726 B4DVL4
AK301354 BAG62899 B4DW37
AK301190 BAH13427 B7Z6Z1
V00523 CAA23782 P01903
V00528 CAA23787 Q29868
CR457013 CAG33294 P01903

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens HLA-DRA NP_061984 R.norvegicus RT1-Da 294269   NP_001008847 77
M.musculus H2-Ea-ps 100504404 Gene Info XP_003085197 73

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta