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Gene Info

Gene Information For:Hs. NEU1, sialidase 1 (lysosomal sialidase)
Sequence ID:NM_000434
RefSeqGene ID:NG_008201
Entrez Gene ID:4758
Ensembl ID:ENSG00000204386

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, retina, skin, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
SIALIDOSIS, TYPE I 

Cytogenetic Location (from UniGene)

Cytogenetic Location:6p21.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:6: 31826979 - 31830683

NM_000434 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
199113182682931827721
91211343182781831828040
113513173182821531828397
131815803182896431829226
158117733182977531829967
177420883183039431830708

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3506824Full LengthBC000722sialidase 1 (lysosomal sialidase)
4101695Full LengthBC011900sialidase 1 (lysosomal sialidase)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000425  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_000434 NP_000425 Q5JQI0
Q99519
EC 3.2.1.18 BNR

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
AF040958 AAB96774 Q5JQI0
Q99519
EC 3.2.1.18
U84246 AAD09239 Q5JQI0
Q99519
EC 3.2.1.18
BC000722 AAH00722 Q5JQI0
Q99519
EC 3.2.1.18
BC011900 AAH11900 Q5JQI0
Q99519
EC 3.2.1.18
BT007206 AAP35870 Q5JQI0
Q99519
EC 3.2.1.18
DQ890716 ABM81642    
DQ892186 ABM83112    
DQ893896 ABM84822    
DQ895380 ABM86306    
AB209011 BAD92248 Q59GU8  
AK290966 BAF83655 A8K4K1  
AK313006 BAG35842 Q5JQI0  
X78687 CAA55356 Q5JQI0
Q99519
EC 3.2.1.18
CR456717 CAG32998 Q6IBT5  
CR541916 CAG46714 Q5JQI0
Q99519
EC 3.2.1.18

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens NEU1 NP_000425 M.musculus Neu1 18010 Gene Info NP_035023 84
R.norvegicus Neu1 24591   NP_113710 84

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)