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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. AFF4, AF4/FMR2 family, member 4
Sequence ID:NM_014423
RefSeqGene ID:NG_030340
Entrez Gene ID:27125
Ensembl ID:ENSG00000072364

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, retina, skin, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:5q31Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:5: 132227508 - 132299310

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
9021223Full LengthBC137226AF4/FMR2 family, member 4
6167752IncompleteBC100287AF4/FMR2 family, member 4

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_055238  

Protein Infomation

NM_014423 NP_055238 Q9UHB7 AF-4

Related Sequences

AF197927 AAF18981 Q9UHB7
AF161355 AAF28915 Q9UHB7
BC025700 AAH25700 Q8TAX5
BC063007 AAH63007 Q9UHB7
BC100287 AAI00288 Q9UHB7
BC137226 AAI37227 Q9UHB7
AF213987 AAM00184 Q9UHB7
AF173886 AAQ13633 Q7Z2T0
AB209547 BAD92784 Q9UHB7

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens AFF4 NP_055238 M.musculus Aff4 93736 Gene Info NP_291043 94
R.norvegicus Aff4 303132   NP_001100471 94
D.melanogaster lilli 33496   NP_001137772 26

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)