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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. TLR2, toll-like receptor 2
Sequence ID:NM_003264
RefSeqGene ID:NG_016229
Entrez Gene ID:7097

Database Links

UniGeneEntrez GeneOMIMHPRDSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
COLON CANCERAKT1
APC
APC
AURKA
AXIN2
BCL10
BUB1B
CCND1
EP300
FGFR3
FLCN
MLH3
NRAS
ODC1
PDGFRL
PIK3CA
PIK3CA
PLA2G2A
PTPRJ
SMAD7
TLR4
TP53
TP53
LEPROSYTLR1
TLR1

Cytogenetic Location (from UniGene)

Cytogenetic Location:4q32Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:4: 154624059 - 154626414

NM_003264 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
172154605440154605511
73203154609068154609198
2043400154624043154627239

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
5213439Full LengthBC033756toll-like receptor 2

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_003255  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_003264 NP_003255 O60603 LRR_1
LRRCT
TIR

Related Sequences

 
mRNAGenPeptSwissProt
U88878 AAC34133 O60603
AF051152 AAC34377 O60603
BC033756 AAH33756 O60603
AF502291 AAM23001 O60603
DQ012265 AAY85644 O60603
DQ012266 AAY85645 O60603
DQ012267 AAY85646 O60603
DQ012268 AAY85647 O60603
DQ012269 AAY85648 O60603
DQ012270 AAY85649 O60603
DQ012271 AAY85650 O60603
DQ894005 ABM84931  
EU176198 ABW03649  
AK125659 BAG54231 B3KWR9
AB445624 BAG55021 O60603

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens TLR2 NP_003255 R.norvegicus Tlr2 310553   NP_942064 72
M.musculus Tlr2 24088 Gene Info NP_036035 71

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)