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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. WFS1, Wolfram syndrome 1 (wolframin)
Sequence ID:NM_001145853
NM_006005
RefSeqGene ID:NG_011700
Entrez Gene ID:7466
Ensembl ID:ENSG00000109501

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
DEAFNESS, AUTOSOMAL DOMINANT 6/14/38 
DIABETES MELLITUS, NON-INSULIN-DEPENDENTABCC8
AKT2
CDKAL1
ENPP1
GCGR
GCK
GPD2
HMGA1
HMGA1
HNF1A
HNF1B
HNF4A
IGF2BP2
IL6
IRS1
IRS2
KCNJ11
LIPC
MAPK8IP1
MTNR1B
NEUROD1
NEUROD1
NEUROD1
PAX4
PDX1
PPARG
PTPN1
RETN
SLC2A4
SLC30A8
TCF7L2
VEGFA
WOLFRAM SYNDROME 
WOLFRAM-LIKE SYNDROME, AUTOSOMAL DOMINANTTET2
TET2

Cytogenetic Location (from UniGene)

Cytogenetic Location:4p16.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:4: 6271576 - 6304992

 Exon Info From UCSC:
NM_001145853
NM_006005

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4127654Full LengthBC030130Wolfram syndrome 1 (wolframin)

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_001145853 NP_001139325    
NM_006005 NP_005996 O76024  

Related Sequences

 
mRNAGenPeptSwissProt
AF084481 AAC64943 O76024
BC030130 AAH30130 O76024
EU176760 ABW03561  
AK312897 BAG35744 O76024
AK295986 BAG58761 B4DJ99
Y18064 CAA77022 O76024

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens WFS1 NP_001139325 M.musculus Wfs1 22393 Gene Info NP_035846 87
R.norvegicus Wfs1 83725   NP_114011 87

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)