Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. PAK2, p21 protein (Cdc42/Rac)-activated kinase 2
Sequence ID:NM_002577
RefSeqGene ID:NG_009227
Entrez Gene ID:5062
Ensembl ID:ENSG00000180370

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, pineal gland, placenta, pooled tissue, prostate, retina, skin, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:3q29Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:3: 196466843 - 196555886

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
7262289Full LengthBC069613p21 protein (Cdc42/Rac)-activated kinase 2
6058556IncompleteBC046197p21 (CDKN1A)-activated kinase 2

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002568  

Protein Infomation

NM_002577 NP_002568 Q13177 EC Pkinase

Related Sequences

U24153 AAA65442 Q13177 EC
U25975 AAA75468 Q13177 EC
BC069613 AAH69613 Q13177 EC
AK291339 BAF84028 A8K5M4  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens PAK2 NP_002568 R.norvegicus Pak2 29432   NP_445758 97
M.musculus Pak2 224105 Gene Info NP_796300 97

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta