Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
Genes
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. GLUL, glutamate-ammonia ligase
Sequence ID:NM_001033044
NM_001033056
NM_002065
RefSeqGene ID:NG_013347
Entrez Gene ID:2752
Ensembl ID:ENSG00000135821

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pineal gland, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
GLUTAMINE DEFICIENCY, CONGENITAL 

Cytogenetic Location (from UniGene)

Cytogenetic Location:1q31Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:1: 182353415 - 182361341

 Exon Info From UCSC:
NM_001033044
NM_001033056
NM_002065

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3352740Full LengthBC018992glutamate-ammonia ligase (glutamine synthetase)
3528830Full LengthBC011700glutamate-ammonia ligase (glutamine synthetase)
3545927Full LengthBC010037glutamate-ammonia ligase (glutamine synthetase)
4137547Full LengthBC011852glutamate-ammonia ligase (glutamine synthetase)
4837475Full LengthBC031964glutamate-ammonia ligase (glutamine synthetase)
5261804Full LengthBC051726glutamate-ammonia ligase (glutamine synthetase)
40131529IncompleteBC127883glutamate-ammonia ligase (glutamine synthetase)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002056  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001033044 NP_001028216 P15104 EC 6.3.1.2
EC 4.1.1.15
 
NM_001033056 NP_001028228 P15104 EC 6.3.1.2
EC 4.1.1.15
 
NM_002065 NP_002056 P15104 EC 6.3.1.2
EC 4.1.1.15
Gln-synt_C
Gln-synt_N

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
S70290 AAB30693 P15104 EC 6.3.1.2
EC 4.1.1.15
BC010037 AAH10037 P15104 EC 6.3.1.2
EC 4.1.1.15
BC011700 AAH11700 P15104 EC 6.3.1.2
EC 4.1.1.15
BC011852 AAH11852 P15104 EC 6.3.1.2
EC 4.1.1.15
BC018992 AAH18992 P15104 EC 6.3.1.2
EC 4.1.1.15
BC031964 AAH31964 P15104 EC 6.3.1.2
EC 4.1.1.15
BC051726 AAH51726 P15104 EC 6.3.1.2
EC 4.1.1.15
BC127883 AAI27884 A1L199  
AY486122 AAS57904 P15104 EC 6.3.1.2
EC 4.1.1.15
AY513283 AAT08036 Q2TU80  
AY947343 AAY57874 A8YXX4  
DQ893278 ABM84204    
DQ896609 ABM87608    
EU832735 ACE87067    
EU832658 ACE87749    
AK092874 BAG52617 Q9NSP3  
AK122784 BAG53728 A8YXX4  
AK301600 BAG63088 B4DWM6  
X59834 CAA42495 P15104 EC 6.3.1.2
EC 4.1.1.15
Y00387 CAA68457 P15104 EC 6.3.1.2
EC 4.1.1.15
AL161952 CAB82304 Q9NSP3  
BX537384 CAD97626 P15104 EC 6.3.1.2
EC 4.1.1.15

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens GLUL NP_001028216 M.musculus Glul 14645 Gene Info NP_032157 95
A.gambiae AgaP_AGAP002355 1273608   XP_312603 66
D.melanogaster Gs2 32087   NP_727525 66
C.elegans gln-3 178452   NP_001041009 65
N.crassa NCU06724 3877042   XP_960904 61
S.pombe gln1 2541752   NP_593400 57
A.thaliana GLN1.3 821050   NP_188409 57
S.cerevisiae GLN1 856147   NP_015360 57

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)