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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. EIF4A2, eukaryotic translation initiation factor 4A2
Sequence ID:NM_001967
Entrez Gene ID:1974
Ensembl ID:ENSG00000156976

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pineal gland, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:3q28Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:3: 186505580 - 186506074

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4079371Full LengthBC012547eukaryotic translation initiation factor 4A, isoform 2
4337581Full LengthBC015842eukaryotic translation initiation factor 4A, isoform 2
4341420Full LengthBC013708eukaryotic translation initiation factor 4A, isoform 2
4820774Full LengthBC048105eukaryotic translation initiation factor 4A, isoform 2
5269135IncompleteBC039344eukaryotic translation initiation factor 4A, isoform 2

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_001958  

Protein Infomation

NM_001967 NP_001958 Q14240 EC DEAD

Related Sequences

AF208852 AAF64266 Q9NZE6  
BC012547 AAH12547 Q14240 EC
BC013708 AAH13708 Q14240 EC
BC015842 AAH15842 Q14240 EC
BC016295 AAH16295 Q96B07  
BC048105 AAH48105 Q14240 EC
AY207392 AAO66460 Q86WD0  
BT009860 AAP88862 Q14240 EC
DQ891738 ABM82664    
DQ894914 ABM85840    
D30655 BAA06336 Q14240 EC
AB209021 BAD92258 Q59GT8  
AK296279 BAG58988 B4DJX6  
AL117412 CAI46218 Q5JWW0  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens EIF4A2 NP_001958 R.norvegicus Eif4a2 303831   NP_001008336 100
M.musculus Eif4a2 13682 Gene Info NP_038534 100
A.gambiae AgaP_AGAP009863 1279280   XP_318978 75
D.melanogaster eIF-4a 33835   NP_476595 74
A.thaliana EIF4A1 820605   NP_566469 73
C.elegans inf-1 175966   NP_001022623 72
A.thaliana EIF4A-2 841868   NP_175829 72
P.falciparum H45 812237   XP_001348829 69

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta