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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. SOX2, SRY (sex determining region Y)-box 2
Sequence ID:NM_003106
RefSeqGene ID:NG_009080
Entrez Gene ID:6657
Ensembl ID:ENSG00000181449

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
MICROPHTHALMIA, SYNDROMIC 3 

Cytogenetic Location (from UniGene)

Cytogenetic Location:3q26.3-q27Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:3: 181429713 - 181431102

NM_003106 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
12500181429721181432220

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2823424Full LengthBC013923SRY (sex determining region Y)-box 2

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_003097  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_003106 NP_003097 P48431 HMG_box

Related Sequences

 
mRNAGenPeptSwissProt
L07335 AAA35997 P48431
BC013923 AAH13923 P48431
EU446654 ABZ92183  
Z31560 CAA83435 P48431

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens SOX2 NP_003097 M.musculus Sox2 20674 Gene Info NP_035573 98
R.norvegicus Sox2 499593   NP_001102651 98

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)