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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. SCN5A, sodium channel, voltage-gated, type V, alpha subunit
Sequence ID:NM_000335
NM_001099404
NM_001099405
NM_001160160
NM_001160161
NM_198056
RefSeqGene ID:NG_008934
Entrez Gene ID:6331
Ensembl ID:ENSG00000183873

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
ATRIAL FIBRILLATION, FAMILIAL, 10 
BRUGADA SYNDROME 1 
CARDIOMYOPATHY, DILATED, 1E 
HEART BLOCK, NONPROGRESSIVE 
LONG QT SYNDROME-3 
SICK SINUSSYNDROME 1 
SUDDEN INFANT DEATH SYNDROME 
VENTRICULAR FIBRILLATION, FAMILIAL, 1 

Cytogenetic Location (from UniGene)

Cytogenetic Location:3p21Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:3: 38591458 - 38674840

 Exon Info From UCSC:
NM_000335
NM_001099404
NM_001099405
NM_001160160
NM_001160161
NM_198056

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
9021681Full LengthBC140813sodium channel, voltage-gated, type V, alpha subunit
9053152Full LengthBC144621sodium channel, voltage-gated, type V, alpha subunit

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000326  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_000335 NP_000326   Ion_trans
Na_trans_assoc
NM_001099404 NP_001092874    
NM_001099405 NP_001092875    
NM_001160160 NP_001153632    
NM_001160161 NP_001153633    
NM_198056 NP_932173 Q14524  

Related Sequences

 
mRNAGenPeptSwissProt
M77235 AAA58644 Q14524
BC051374 AAH51374 Q86V90
BC140813 AAI40814 Q14524
BC144621 AAI44622 Q14524
AY038064 AAK74065 Q14524
AY148488 AAN61120 Q14524
AF482988 AAO91669 Q14524
EF092293 ABN50062 A3EY19
EF092294 ABN50063 A3EY20
EF092295 ABN50064 A3EY21
EF629346 ABR15763 Q14524
EF629347 ABR15764 Q14524
GU014840 ACX32327 Q14524
AB158469 BAD12084 Q14524
AB158470 BAD12085 Q14524
AB208866 BAD92103 Q14524
AJ310893 CAC84525 Q8WWN6
AJ310886 CAC84529 Q8WTS0
AJ310887 CAC84530 Q8WTS0
AJ310888 CAC84531 Q8WTS0
AJ310889 CAC84532 Q8WTS0
AJ310890 CAC84533 Q8WTQ6
AJ310891 CAC84534 Q8WTQ6
AJ310892 CAC84535 Q8WTS0
AJ310896 CAC84536 Q8WWN5

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens SCN5A NP_001092874 M.musculus Scn5a 20271 Gene Info NP_067519 95
R.norvegicus Scn5a 25665   NP_037257 94

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)