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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. RAC2, Ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
Sequence ID:NM_002872
RefSeqGene ID:NG_007288
Entrez Gene ID:5880
Ensembl ID:ENSG00000128340

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
NEUTROPHIL IMMUNODEFICIENCY SYNDROME 

Cytogenetic Location (from UniGene)

Cytogenetic Location:22q13.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:22: 37621300 - 37622035

NM_002872 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
518183762131137622078
8199513762271037622842
95211113762727037627429
111211743762797137628033
117512923762884037628957
129313643763762637637697
136515163764015337640304

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3509104Full LengthBC001485ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
4428246IncompleteBC051899ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
4874755IncompleteBC018735ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002863  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_002872 NP_002863 P15153 Ras

Related Sequences

 
mRNAGenPeptSwissProt
M29871 AAA36538 P15153
AF077208 AAD27003  
BC001485 AAH01485 P15153
AF498965 AAM21112 P15153
BT006919 AAP35565 P15153
DQ893288 ABM84214  
DQ896620 ABM87619  
EU176461 ABW03912  
CR456555 CAG30441 P15153
CU013155 CAK54586  
CU013443 CAK54885  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens RAC2 NP_002863 M.musculus Rac2 19354 Gene Info NP_033034 99
R.norvegicus Rac2 366957   NP_001008385 99
A.thaliana RAC10 836408   NP_201093 61
A.thaliana ROP10 823959   NP_566897 59

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)