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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. MCM5, minichromosome maintenance complex component 5
Sequence ID:NM_006739
Entrez Gene ID:4174
Ensembl ID:ENSG00000100297

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, pituitary gland, placenta, pooled tissue, prostate, salivary gland, skin, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:22q13.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:22: 35796138 - 35820494

 Exon Info From UCSC:
NM_006739

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2900229Full LengthBC000142minichromosome maintenance complex component 5
3542201Full LengthBC003656minichromosome maintenance complex component 5

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_006730  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_006739 NP_006730 P33992 EC 3.6.4.12 MCM

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
BC000142 AAH00142 P33992 EC 3.6.4.12
BC003656 AAH03656 P33992 EC 3.6.4.12
D83986 BAA12176 P33992 EC 3.6.4.12
AB209612 BAD92849 Q59F49  
AK223323 BAD97043 Q53FG5  
AK291136 BAF83825 A8K521  
AK312533 BAG35432 B1AHB0  
AK122853 BAG53762 B3KVF0  
AK298624 BAG60801 B4DQ39  
AK301121 BAG62717 B4DVK5  
X74795 CAA52802 P33992 EC 3.6.4.12
CR456517 CAG30403 P33992 EC 3.6.4.12
CU013117 CAK54548    
CU013405 CAK54847    

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens MCM5 NP_006730 R.norvegicus Mcm5 291885   NP_001099640 97
M.musculus Mcm5 17218 Gene Info NP_032592 96
A.gambiae AgaP_AGAP004408 1274553   XP_313694 70
D.melanogaster Mcm5 41296   NP_524308 70
C.elegans mcm-5 175552   NP_497858 64
S.cerevisiae MCM5 850980   NP_013376 51
N.crassa NCU01171 3877733   XP_961537 51
A.thaliana MCM5 815415   NP_178812 50

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta