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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. EP300, E1A binding protein p300
Sequence ID:NM_001429
RefSeqGene ID:NG_009817
Entrez Gene ID:2033
Ensembl ID:ENSG00000100393

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
COLON CANCERAKT1
APC
APC
AURKA
AXIN2
BCL10
BUB1B
CCND1
FGFR3
FLCN
MLH3
NRAS
ODC1
PDGFRL
PIK3CA
PIK3CA
PLA2G2A
PTPRJ
SMAD7
TLR2
TLR4
TP53
TP53
RUBINSTEIN-TAYBI SYNDROMECREBBP

Cytogenetic Location (from UniGene)

Cytogenetic Location:22q13.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:22: 41554471 - 41556423

 Exon Info From UCSC:
NM_001429

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
6151364IncompleteBC053889E1A binding protein p300
100068974BC172280E1A binding protein p300

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_001420  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001429 NP_001420 Q09472 EC 2.3.1.48 Bromodomain
ZZ
zf-TAZ
KIX
DUF902
DUF906

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
U01877 AAA18639 Q09472 EC 2.3.1.48
BC053889 AAH53889 Q7Z6C1  
BC172280 AAI72280    
AB385004 BAG10860    

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens EP300 NP_001420 M.musculus Ep300 328572 Gene Info NP_808489 94
R.norvegicus Ep300 170915   XP_576312 94
A.gambiae AgaP_AGAP000029 1272249   XP_311133 55
D.melanogaster nej 43856   NP_524642 46
C.elegans cbp-1 176380   NP_499161 44

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta