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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. PPOX, protoporphyrinogen oxidase
Sequence ID:NM_000309
RefSeqGene ID:NG_012877
Entrez Gene ID:5498
Ensembl ID:ENSG00000143224

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer Aberrations

Gene Expression Data

Associated Diseases (from OMIM)

DiseaseOther Genes

Cytogenetic Location (from UniGene)

Cytogenetic Location:1q22Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:1: 161136300 - 161146906

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2821983Full LengthBC002357protoporphyrinogen oxidase

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000300  

Protein Infomation

NM_000309 NP_000300 P50336 EC Amino_oxidase
NM_001122764 NP_001116236      

Related Sequences

U26446 AAA67690 P50336 EC
BC002357 AAH02357 P50336 EC
DQ892215 ABM83141    
DQ895411 ABM86337    
D38537 BAA07538 P50336 EC
AK094855 BAG52942 B3KT30  
AK298912 BAG61019 B4DQQ7  
AK302298 BAG63638 B4DY76  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens PPOX NP_000300 M.musculus Ppox 19044 Gene Info NP_032937 89
R.norvegicus Ppox 289219   NP_001099438 88
A.gambiae AgaP_AGAP003704 1274381   XP_313497 41
D.melanogaster Ppox 42939   NP_651278 40
S.pombe hem14 2541631   NP_592866 34
A.thaliana PPOX 827991   NP_192078 32
N.crassa NCU09113 3874470   XP_958322 31
S.cerevisiae HEM14 856733   NP_010930 27

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)