Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
Genes
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. PRODH, Proline dehydrogenase (oxidase) 1
Sequence ID:NM_016335
NM_001195226
RefSeqGene ID:NG_008226
Entrez Gene ID:5625
Ensembl ID:ENSG00000100033

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
HYPERPROLINEMIA, TYPE I 
SCHIZOPHRENIA, SUSCEPTIBILITYTO, 4 

Cytogenetic Location (from UniGene)

Cytogenetic Location:22q11.21Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:22: 18900294 - 18923655


Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
40108132Full LengthBC118597proline dehydrogenase (oxidase) 1
40108133Full LengthBC121809proline dehydrogenase (oxidase) 1
4792060IncompleteBC094736proline dehydrogenase (oxidase) 1
5264431IncompleteBC036534proline dehydrogenase (oxidase) 1
5311991IncompleteBC068260proline dehydrogenase (oxidase) 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_057419  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_001195226 NP_001182155    
NM_016335 NP_057419   Pro_dh

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
AF010310 AAC39529 O43272 EC 1.5.99.8
U79754 AAF21464 O43272 EC 1.5.99.8
BC068260 AAH68260 O43272 EC 1.5.99.8
BC094736 AAH94736 O43272 EC 1.5.99.8
BC118597 AAI18598 O43272 EC 1.5.99.8
BC121809 AAI21810 O43272 EC 1.5.99.8
AB209472 BAD92709 O43272 EC 1.5.99.8

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens PRODH NP_057419 M.musculus Prodh 19125 Gene Info NP_035302 82
R.norvegicus Prodh 680409   NP_001129250 81
A.gambiae AgaP_AGAP003860 1271596   XP_310420 53
D.melanogaster slgA 33117   NP_996528 49
C.elegans B0513.5 178350   NP_502669 47

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)