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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. NCSTN, nicastrin
Sequence ID:NM_015331
RefSeqGene ID:NG_027935
Entrez Gene ID:23385
Ensembl ID:ENSG00000162736

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, placenta, pooled tissue, prostate, retina, skin, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:1q22-q23Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:1: 160313061 - 160328738

 Exon Info From UCSC:
NM_015331

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4827966Full LengthBC047621nicastrin

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_056146  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_015331 NP_056146 Q92542 Nicastrin

Related Sequences

 
mRNAGenPeptSwissProt
AF240468 AAG11412 Q92542
BC047621 AAH47621 Q92542
AY359120 AAQ89478 Q92542
JF432369 ADZ15586  
D87442 BAA13383 Q92542
AK314764 BAG37302 Q92542
AK296153 BAG58892 B4DJN0
AK299142 BAG61194 B4DR82

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens NCSTN NP_056146 M.musculus Ncstn 59287 Gene Info NP_067620 89
R.norvegicus Ncstn 289231   NP_777353 89
A.gambiae AgaP_AGAP001734 1281441   XP_321352 34
D.melanogaster nct 42964   NP_001163713 34
A.thaliana AT3G52640 824430   NP_974419 28
C.elegans aph-2 172905   NP_492712 26

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)