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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. D2HGDH, D-2-hydroxyglutarate dehydrogenase
Sequence ID:NM_152783
RefSeqGene ID:NG_012012
Entrez Gene ID:728294
Ensembl ID:ENSG00000180902

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer Aberrations

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:2q37.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:2: 242693935 - 242708226

NM_152783 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
181242674029242674109
82465242674547242674930
466523242680447242680504
524663242681849242681988
664857242683036242683229
8581026242684123242684291
10271170242689565242689708
11711313242690660242690802
13141479242695263242695428
14802586242707124242708230

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
5274813Full LengthBC036604D-2-hydroxyglutarate dehydrogenase
30334929Full LengthBC071598D-2-hydroxyglutarate dehydrogenase
4745476IncompleteBC031817D-2-hydroxyglutarate dehydrogenase

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_689996  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_152783 NP_689996 Q8N465 FAD_binding_4
FAD-oxidase_C

Related Sequences

 
mRNAGenPeptSwissProt
BC036604 AAH36604 Q8N465
BC071598 AAH71598 Q8N465
AF318334 AAL55841 Q8WYW4
AK124189 BAC85798 Q6ZVR3
AK315188 BAG37628 B2RCN1
AK055846 BAG51584 B3KP72
AK091725 BAG52404 B3KRJ2
AK094149 BAG52828 B3KSR6
AK096060 BAG53205 B3KTU3
AK304764 BAG65519 B4E3K7
AK304773 BAG65528 B4E3L6

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens D2HGDH NP_689996 R.norvegicus D2hgdh 301624   NP_001100396 84
M.musculus D2hgdh 98314 Gene Info NP_849213 82
A.thaliana AT4G36400 829792   NP_568003 58
A.gambiae AgaP_AGAP004195 1274029   XP_313089 56
N.crassa NCU06441 3873501   XP_957332 56
S.cerevisiae DLD2 851376   NP_010103 55
S.pombe SPBC713.03 2541151   NP_595342 51
D.melanogaster CG3835 31184   NP_569982 51
C.elegans F54D5.12 174764   NP_496465 46

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)