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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. SMPD4, sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3)
Sequence ID:NM_001171084
NM_001171083
NM_017751
NM_017951
NR_033230
NR_033231
NR_033232
Entrez Gene ID:55627
Ensembl ID:ENSG00000136699

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:2q21.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:2: 130908981 - 130940323

 Exon Info From UCSC:
NM_001171083
NM_017751
NM_017951

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
6023304Full LengthBC064947sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3)
5590452IncompleteBC040941hypothetical protein FLJ20297

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001171083 NP_001164554      
NM_017751 NP_060221 Q9NXE4 EC 3.1.4.12  
NM_017951 NP_060421      
NM_025029 NP_079305 Q6NZ67    

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
BC014255 AAH14255 Q6NZ67  
BC064947 AAH64947 Q9NXE4 EC 3.1.4.12
BC066296 AAH66296 Q6NZ67  
EU367941 ACA48221 B1PBA3  
HQ448337 ADQ32817    
AK000304 BAA91070 Q9NXE4 EC 3.1.4.12
AK000763 BAA91368 Q9NXE4 EC 3.1.4.12
AK001227 BAA91567 Q9NXE4 EC 3.1.4.12
AB037839 BAA92656 Q9NXE4 EC 3.1.4.12
AK126920 BAC86751 Q9NXE4 EC 3.1.4.12
AK297257 BAG59735 B4DM23  
AK298609 BAG60793 B4DQ31  
AK299185 BAG61230 Q9NXE4 EC 3.1.4.12
AK301576 BAG63069 B4DWK7  
AK303427 BAG64478 B4E0L6  
AK303519 BAG64547 B4E0T5  
AL136737 CAB66671 Q9NXE4 EC 3.1.4.12
CR533550 CAG38581 Q9NXE4 EC 3.1.4.12

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens SMPD4 NP_060421 R.norvegicus Smpd4 303790   NP_001161278 91
M.musculus Smpd4 77626 Gene Info NP_001158082 90
A.gambiae AgaP_AGAP000405 1271841   XP_310695 32
D.melanogaster CG6962 41436   NP_650124 29

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)