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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. SMEK2, SMEK homolog 2, suppressor of mek1 (Dictyostelium)
Sequence ID:NM_001122964
Entrez Gene ID:57223
Ensembl ID:ENSG00000138041

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:2p16.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:2: 55775514 - 55844723

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3140319Full LengthBC006215SMEK homolog 2, suppressor of mek1 (Dictyostelium)
5259789Full LengthBC060855SMEK homolog 2, suppressor of mek1 (Dictyostelium)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_065196  

Protein Infomation

NM_001122964 NP_001116436 Q5MIZ7  
NM_020463 NP_065196   DUF625

Related Sequences

BC006215 AAH06215 Q5MIZ7
BC045714 AAH45714 Q5MIZ7
BC060855 AAH60855 Q5MIZ7
AY825268 AAV97750 Q5MIZ7
AY825269 AAV97751 Q5MIZ7
AB037808 BAA92625 Q5MIZ7
AK023148 BAB14430 Q5MIZ7
AK296481 BAG59121 B4DKA9
AL136556 CAB66491 Q5MIZ7

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens SMEK2 NP_001116436 R.norvegicus Smek2 360993   NP_001101837 98
M.musculus Smek2 104570 Gene Info NP_598795 97

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)