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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. MAT2A, methionine adenosyltransferase II, alpha
Sequence ID:NM_005911
RefSeqGene ID:NG_029183
Entrez Gene ID:4144
Ensembl ID:ENSG00000168906

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pineal gland, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:2p11.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:2: 85766292 - 85771149

NM_005911 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
12148576628785766500
2152928576820585768282
2934158576837785768499
4165288576875585768867
5296728576895185769094
6738918576927785769495
89210748576968785769869
107512088577002385770156
120928178577079285772400

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3010820Full LengthBC001686methionine adenosyltransferase II, alpha
3010820Full LengthBC001854methionine adenosyltransferase II, alpha

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_005902  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_005911 NP_005902 P31153 EC 2.5.1.6 S-AdoMet_synt_N
S-AdoMet_synt_M
S-AdoMet_synt_C

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
BC001686 AAH01686 P31153 EC 2.5.1.6
BC001854 AAH01854 P31153 EC 2.5.1.6
DQ083239 AAY85355 P31153 EC 2.5.1.6
JF432119 ADZ15336    
AK291126 BAF83815 P31153 EC 2.5.1.6
AK293841 BAG57239 B4DEX8  
AK297758 BAG60107 B4DN45  
AK297797 BAG60136 B4DN74  
AK303877 BAG64814 B4E1K2  
AK316411 BAH14782 B4DN45  
X68836 CAA48726 P31153 EC 2.5.1.6

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens MAT2A NP_005902 M.musculus Mat2a 232087 Gene Info NP_663544 99
R.norvegicus Mat2a 171347   NP_599178 98
D.melanogaster Sam-S 48552   NP_995602 75
A.gambiae AgaP_AGAP009447 1269245   XP_307863 74
C.elegans Y105C5B.12 178446   NP_872083 74
C.elegans C06E7.3 177354   NP_500871 74
C.elegans C06E7.1 177355   NP_500872 74
C.elegans tag-32 177389   NP_741415 72
N.crassa NCU02657 3881571   XP_965430 71
S.pombe sam1 2539943   NP_596731 70
C.elegans sams-1 181370   NP_510002 68
S.cerevisiae SAM1 850877   NP_013281 68
S.cerevisiae SAM2 852113   NP_010790 68
A.thaliana MAT3 818260   NP_181225 67

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)