Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
Genes
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. HADHB, hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit
Sequence ID:NM_000183
RefSeqGene ID:NG_007294
Entrez Gene ID:3032
Ensembl ID:ENSG00000138029

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
TRIFUNCTIONAL PROTEIN DEFICIENCYHADHA

Cytogenetic Location (from UniGene)

Cytogenetic Location:2p23Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:2: 26467809 - 26513333

 Exon Info From UCSC:
NM_000183

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2988132Full LengthBC017564hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit
3960772Full LengthBC014572hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit
4288635Full LengthBC030824hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit
4796447Full LengthBC066963hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000174  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_000183 NP_000174 P55084 EC 2.3.1.16 Thiolase_N
Thiolase_C

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
AF113209 AAG39280 P55084 EC 2.3.1.16
BC014572 AAH14572 P55084 EC 2.3.1.16
BC017564 AAH17564 P55084 EC 2.3.1.16
BC030824 AAH30824 P55084 EC 2.3.1.16
BC066963 AAH66963 P55084 EC 2.3.1.16
DQ892722 ABM83648    
DQ895971 ABM86897    
D16481 BAA03942 P55084 EC 2.3.1.16
AK314455 BAG37063 P55084 EC 2.3.1.16
AK293142 BAG56690 B4DDC9  
AK302322 BAG63658 B4DY96  
AK304455 BAG65272 B4E2W0  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens HADHB NP_000174 M.musculus Hadhb 231086 Gene Info NP_663533 91
R.norvegicus Hadhb 171155   NP_598302 90
A.gambiae AgaP_AGAP011827 1280821   XP_320688 72
D.melanogaster Thiolase 37784   NP_477378 69
C.elegans B0303.3 176216   NP_498915 62

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)