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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. SAE1, SUMO1 activating enzyme subunit 1
Sequence ID:NM_001145713
Entrez Gene ID:10055
Ensembl ID:ENSG00000142230

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:19q13.32Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:19: 47634143 - 47713532

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2823028Full LengthBC000344SUMO1 activating enzyme subunit 1
2988252Full LengthBC003611SUMO1 activating enzyme subunit 1
3452340Full LengthBC018271SUMO1 activating enzyme subunit 1

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_005491  

Protein Infomation

NM_001145713 NP_001139185    
NM_001145714 NP_001139186    
NM_005500 NP_005491 Q9UBE0 ThiF

Related Sequences

AF090385 AAD12785 Q9UBE0
AF046025 AAD23902 Q9UBE0
AF110956 AAD24433 Q9UBE0
AF161489 AAF29104 Q9UBE0
BC000344 AAH00344 Q9UBE0
BC003611 AAH03611 Q9UBE0
BC018271 AAH18271 Q9UBE0
BT007290 AAP35954 Q9UBE0
DQ891751 ABM82677  
DQ894932 ABM85858  
AK315624 BAG37992 Q9UBE0
AK021978 BAG51064 B3KMQ2
AK027595 BAG51356 B3KNJ4
AK302287 BAG63628 B4DY66

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens SAE1 NP_005491 M.musculus Sae1 56459 Gene Info NP_062722 93
R.norvegicus Sae1 308384   NP_001012063 92
A.gambiae AgaP_AGAP004459 1274605   XP_313754 46
D.melanogaster Aos1 41532   NP_650198 41
A.thaliana SAE1A 828596   NP_567712 37
A.thaliana SAE1B 835127   NP_851162 37
A.thaliana SAE1B 835139   NP_001032050 37
S.cerevisiae AOS1 856310   NP_015506 37
N.crassa NCU09006 3875156   XP_959034 36
S.pombe rad31 2543606   NP_593251 34
C.elegans aos-1 179409   NP_505604 32

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta