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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. UPF1, UPF1 regulator of nonsense transcripts homolog (yeast)
Sequence ID:NM_002911
Entrez Gene ID:5976
Ensembl ID:ENSG00000005007

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:19p13.2-p13.11Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:19: 18942794 - 18979039

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
5555509Full LengthBC039817UPF1 regulator of nonsense transcripts homolog (yeast)
4775809IncompleteBC034291UPF1 regulator of nonsense transcripts homolog (yeast)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002902  

Protein Infomation

NM_002911 NP_002902   ResIII

Related Sequences

AF074016 AAC26788 Q92900
U65533 AAC50771 Q92900
U59323 AAC51140 Q92900
BC039817 AAH39817 Q92900
D86988 BAA19664 Q92900
AK125797 BAC86297 Q6ZUC8
AK128727 BAG54717 B3KY55

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens UPF1 NP_002902 M.musculus Upf1 19704 Gene Info NP_001116301 99
D.melanogaster Upf1 32153   NP_572767 71
A.gambiae AgaP_AGAP001133 1282033   XP_322028 67
A.thaliana LBA1 834747   NP_199512 64
N.crassa NCU04242 3877396   XP_961233 61
S.pombe upf1 2542327   NP_593080 60
S.cerevisiae NAM7 855104   NP_013797 57
C.elegans smg-2 171696   NP_490829 53

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)