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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. JAK3, Janus kinase 3
Sequence ID:NM_000215
RefSeqGene ID:NG_007273
Entrez Gene ID:3718
Ensembl ID:ENSG00000105639

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:19p13.1Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:19: 17949078 - 17958841

 Exon Info From UCSC:
NM_000215

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
5212575Full LengthBC028068Janus kinase 3 (a protein tyrosine kinase, leukocyte)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_000206  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_000215 NP_000206 P52333 EC 2.7.10.2 Pkinase_Tyr

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
U08340 AAA17743 Q6LD09  
U09607 AAA19626 P52333 EC 2.7.10.2
U31317 AAC50225 Q9UMU1  
U31601 AAC50226 P52333 EC 2.7.10.2
U57096 AAC50542 P52333 EC 2.7.10.2
BC028068 AAH28068 Q8N1E8  
AK296383 BAG59055 B4DK43  
AK304392 BAG65227 B4E2R5  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens JAK3 NP_000206 M.musculus Jak3 16453 Gene Info NP_034719 84
R.norvegicus Jak3 25326   NP_036987 82

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta