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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. AP4B1, adaptor-related protein complex 4, beta 1 subunit
Sequence ID:NM_001253852
RefSeqGene ID:NG_031901
Entrez Gene ID:10717
Ensembl ID:ENSG00000134262

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, colon, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, placenta, pooled tissue, prostate, retina, salivary gland, skin, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:1p13.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:1: 114437677 - 114447482

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2906087Full LengthBC014146adaptor-related protein complex 4, beta 1 subunit

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_006585  

Protein Infomation

NM_001253852 NP_001240781    
NM_001253853 NP_001240782    
NM_006594 NP_006585 Q9Y6B7 Adaptin_N

Related Sequences

AF092094 AAD20448 Q9Y6B7
BC014146 AAH14146 Q9Y6B7
JF432293 ADZ15510  
AB209817 BAD93054 Q9Y6B7
AK314641 BAG37203 B2RBF6
AK093740 BAG52756 B3KSJ4
AK300204 BAG61975 B4DTG3
AK298037 BAH12709 B7Z4X3

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens AP4B1 NP_006585 R.norvegicus Ap4b1 310746   NP_001101179 91
M.musculus Ap4b1 67489 Gene Info NP_001157024 91
A.thaliana AT5G11490 831021   NP_001190290 37
P.falciparum MAL7P1.164 2654988   XP_001349197 33

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)