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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. MKNK2, MAP kinase interacting serine/threonine kinase 2
Sequence ID:NM_017572
NM_199054
RefSeqGene ID:NG_029798
Entrez Gene ID:2872
Ensembl ID:ENSG00000099875

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, pineal gland, placenta, pooled tissue, prostate, retina, skin, soft tissue, spleen, stem cell, stomach, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:19p13.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:19: 2037469 - 2050872

 Exon Info From UCSC:
NM_017572
NM_199054

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
6527053Full LengthBC073140MAP kinase interacting serine/threonine kinase 2
4127624IncompleteBC021235MAP kinase interacting serine/threonine kinase 2

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_951009  NP_060042  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_017572 NP_060042     Pkinase
NM_199054 NP_951009 Q9HBH9 EC 2.7.11.1 Pkinase

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
AF125532 AAF17226 Q9HBH9 EC 2.7.11.1
AF237775 AAG26336 Q9HBH9 EC 2.7.11.1
AF237776 AAG26337 Q9HBH9 EC 2.7.11.1
BC018345 AAH18345 Q9NV89  
BC073140 AAH73140 Q9HBH9 EC 2.7.11.1
EU832396 ACE86881    
EU832311 ACE87568    
AK001730 BAA91866 Q9NV89  
AB209074 BAD92311 Q59GN5  
AK092536 BAG52569 B3KS07  
AK293742 BAG57165 B4DEQ4  
AK303393 BAG64449 B4E0I7  
AL137565 CAB70816 Q9NT28  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens MKNK2 NP_951009 M.musculus Mknk2 17347 Gene Info NP_067437 95
R.norvegicus Mknk2 299618   NP_001011985 94

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta