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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. SMURF2, SMAD specific E3 ubiquitin protein ligase 2
Sequence ID:NM_022739
Entrez Gene ID:64750
Ensembl ID:ENSG00000108854

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer Aberrations

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, muscle, nervous, pancreas, pancreatic islet, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:17q22-q23Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:17: 62541940 - 62658006

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
7939721Full LengthBC093876SMAD specific E3 ubiquitin protein ligase 2
8327413Full LengthBC111945SMAD specific E3 ubiquitin protein ligase 2
3890635IncompleteBC009527SMAD specific E3 ubiquitin protein ligase 2

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_073576  

Protein Infomation

NM_022739 NP_073576 Q9HAU4 C2

Related Sequences

AF301463 AAG25641 Q9HAU4
AF310676 AAG45422 Q9HAU4
AY014180 AAG50421 Q9HAU4
BC009527 AAH09527 Q96DE7
BC093876 AAH93876 Q9HAU4
BC111945 AAI11946 Q9HAU4

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens SMURF2 NP_073576 M.musculus Smurf2 66313 Gene Info NP_079757 99
R.norvegicus Smurf2 303614   NP_001100531 99
D.melanogaster lack 36999   NP_523779 63
A.gambiae AgaP_AGAP011242 1270684   XP_309403 61

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta