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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. MAP2K4, mitogen-activated protein kinase kinase 4
Sequence ID:NM_003010
Entrez Gene ID:6416
Ensembl ID:ENSG00000065559

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:17p12Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:17: 12027615 - 12047047

 Exon Info From UCSC:
NM_003010

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
5272439Full LengthBC036032mitogen-activated protein kinase kinase 4
5294838Full LengthBC060764mitogen-activated protein kinase kinase 4

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_003001  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_003010 NP_003001 P45985 EC 2.7.12.2 Pkinase

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
L36870 AAC41719 P45985 EC 2.7.12.2
U17743 AAC50127 P45985 EC 2.7.12.2
BC036032 AAH36032 P45985 EC 2.7.12.2
BC060764 AAH60764 P45985 EC 2.7.12.2
BT019676 AAV38482 P45985 EC 2.7.12.2
AK313053 BAG35884 P45985 EC 2.7.12.2
AK131544 BAG54774 P45985 EC 2.7.12.2
AK294923 BAG58005 B4DH44  
AK316100 BAH14471 B7Z9Y5  
AK316177 BAH14548 B7ZA62  
CR536564 CAG38801 P45985 EC 2.7.12.2

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens MAP2K4 NP_003001 M.musculus Map2k4 26398 Gene Info NP_033183 98
R.norvegicus Map2k4 287398   NP_001025194 98
A.gambiae AgaP_AGAP003365 1275042   XP_314266 66
D.melanogaster Mkk4 41020   NP_477353 62
C.elegans mkk-4 185682   NP_509682 55
C.elegans VZC374L.1 189074   NP_509683 49
S.cerevisiae PBS2 853313   NP_012407 45
S.pombe wis1 2541055   NP_595457 45
N.crassa NCU00587 3881869   XP_965727 42

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta