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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. SIRT7, Sirtuin 7
Sequence ID:NM_016538
Entrez Gene ID:51547
Ensembl ID:ENSG00000187531

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:17q25Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:17: 79869814 - 79876040

NM_016538 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
196947986981479870489
6958017987164979871755
8028827987196279872042
88311197987216979872405
112012187987247979872577
121912917987331579873387
129213627987348679873556
136314677987549079875594
146816057987570579875842
160617497987591479876057

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
5087554Full LengthBC017305sirtuin (silent mating type information regulation 2 homolog) 7 (S. cerevisiae)
8069297Full LengthBC101791sirtuin (silent mating type information regulation 2 homolog) 7 (S. cerevisiae)
8069299Full LengthBC101793sirtuin (silent mating type information regulation 2 homolog) 7 (S. cerevisiae)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_057622  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_016538 NP_057622 Q9NRC8 SIR2

Related Sequences

 
mRNAGenPeptSwissProt
AF233395 AAF43431 Q9NRC8
BC017305 AAH17305 Q9NRC8
BC101791 AAI01792 Q9NRC8
BC101793 AAI01794 Q9NRC8
DQ892354 ABM83280  
DQ895561 ABM86487  
AK002027 BAA92044 Q9NRC8
AK290265 BAF82954 Q9NRC8
AK094326 BAG52860 Q9NRC8
AL137626 CAB70848 Q9NRC8

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens SIRT7 NP_057622 M.musculus Sirt7 209011 Gene Info NP_694696 95
R.norvegicus Sirt7 303745   NP_001100543 94
A.gambiae AgaP_AGAP001220 1281949   XP_321936 51
A.gambiae AgaP_AGAP001221 3290440   XP_551623 51
D.melanogaster Sirt7 43433   NP_651664 51

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)