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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. GRN, Granulin
Sequence ID:NM_002087
RefSeqGene ID:NG_007886
Entrez Gene ID:2896
Ensembl ID:ENSG00000030582

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    adrenal cortex, b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, ear, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, parathyroid, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, soft tissue, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Associated Diseases (from OMIM)

DiseaseOther Genes
APHASIA, PRIMARY PROGRESSIVE 
CEROID LIPOFUSCINOSIS, NEURONAL, 11 

Cytogenetic Location (from UniGene)

Cytogenetic Location:17q21.32Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:17: 42422647 - 42430470

 Exon Info From UCSC:
NM_002087

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
2821810Full LengthBC000324granulin
3457813Full LengthBC010577granulin

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002078  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_002087 NP_002078 P28799 Granulin

Related Sequences

 
mRNAGenPeptSwissProt
M75161 AAA58617 P28799
AF055008 AAC09359 P28799
BC000324 AAH00324 P28799
BC010577 AAH10577 P28799
AY124489 AAM94026 P28799
BT006844 AAP35490 P28799
AK023348 BAB14535 Q9H8S1
AK222522 BAD96242 Q53HQ8
AK296090 BAG58844 B4DJI2
AK303830 BAG64777 B4E1G5
X62320 CAA44196 P28799

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens GRN NP_002078 M.musculus Grn 14824 Gene Info NP_032201 76
R.norvegicus Grn 29143   NP_058809 76

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta