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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. MAP2K3, mitogen-activated protein kinase kinase 3
Sequence ID:NM_002756
RefSeqGene ID:NG_028256
Entrez Gene ID:5606
Ensembl ID:ENSG00000034152

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, bone marrow, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, esophagus, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, placenta, pooled tissue, prostate, retina, salivary gland, skin, spleen, stem cell, stomach, synovium, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus, vascular
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:17q11.2Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:17: 21188232 - 21217541

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
5215093Full LengthBC032478mitogen-activated protein kinase kinase 3

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002747  NP_659731  

Protein Infomation

NM_002756 NP_002747     Pkinase
NM_145109 NP_659731 P46734
EC Pkinase

Related Sequences

U66839 AAB40652 P46734 EC
L36719 AAC41718 P46734 EC
BC032478 AAH32478 P46734
DQ894188 ABM85114    
GQ225578 ACT33197 C7DUW4  
D87116 BAA13248 P46734
AK223490 BAD97210 Q53EZ9  
AK315505 BAG37889 Q6FI23  
AK093838 BAG52769 P46734 EC
AB451226 BAG70040 Q6FI23  
AB451349 BAG70163 Q6FI23  
CR536514 CAG38752 P46734
CR541793 CAG46592 Q6FHG1  

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens MAP2K3 NP_659731 M.musculus Map2k3 26397 Gene Info NP_032954 97
R.norvegicus Map2k3 303200   NP_001094144 97
A.gambiae AgaP_AGAP000310 1271952   XP_310813 65
D.melanogaster lic 32257   NP_477162 61

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta