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Cancer Genome Characterization Initiative

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Gene Info

Gene Information For:Hs. MC1R, melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
Sequence ID:NM_002386
RefSeqGene ID:NG_012026
Entrez Gene ID:4157
Ensembl ID:ENSG00000258839

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data


Associated Diseases (from OMIM)

DiseaseOther Genes
ALBINISM, BROWNOCULOCUTANEOUSOCA2
MALIGNANT MELANOMA, SOMATICPTEN
MELANOMA, CUTANEOUS MALIGNANT, 5 
UV-INDUCEDSKIN DAMAGE 
[ANALGESIA FROM KAPPA-OPIOID RECEPTOR AGONIST, FEMALE-SPECIFIC] 

Cytogenetic Location (from UniGene)

Cytogenetic Location:16q24.3Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:16: 89984286 - 89987379

NM_002386 exon info from UCSC:

Transcript StartTranscript EndChromosomal Start Chromosomal End
130988998428689987383

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
4298428Full LengthBC007856melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
6267157Full LengthBC080622melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_002377  

Protein Infomation

RefSeq
mRNAProteinSwissProtPfam
NM_002386 NP_002377 Q01726 7tm_1

Related Sequences

 
mRNAGenPeptSwissProt
BC007856 AAH07856 Q01726
BC080622 AAH80622 Q01726
DQ893267 ABM84193  
DQ896597 ABM87596  
AK024232 BAG51277 Q1JUL4
AK054666 BAG51408 B3KNP6
X67594 CAA47865 Q01726

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens MC1R NP_002377 M.musculus Mc1r 17199 Gene Info NP_032585 77

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)